Chad M Thompson Selected Research

Neoplasms (Cancer)

12/2023	Derivation of oral cancer slope factors for hexavalent chromium informed by pharmacokinetic models and in vivo genotoxicity data.
1/2022	Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium.
11/2021	A review of mammalian in vivo genotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment.
8/2021	Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches.
1/2021	Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer Using the Key Characteristics of Carcinogens.
11/2020	Using mechanistic information to support evidence integration and synthesis: a case study with inhaled formaldehyde and leukemia.
11/2020	An updated mode of action and human relevance framework evaluation for Formaldehyde-Related nasal tumors.
1/2020	An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet.
3/2019	Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment.
7/2018	An Adverse Outcome Pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events.

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Chad M Thompson Research Topics

Disease

36	Neoplasms (Cancer) 12/2023 - 08/2008
13	Hyperplasia 01/2020 - 11/2009
11	Carcinogenesis 10/2019 - 09/2011
5	Intestinal Neoplasms (Intestinal Cancer) 01/2021 - 05/2014
4	Asthma (Bronchial Asthma) 03/2010 - 01/2008
3	Adenoma (Adenomas) 05/2024 - 03/2013
3	Carcinoma (Carcinomatosis) 05/2024 - 03/2013
3	Lung Neoplasms (Lung Cancer) 05/2019 - 11/2014
3	Inflammation (Inflammations) 11/2014 - 01/2008
2	Mouth Neoplasms (Oral Cancer) 12/2023 - 01/2019
2	Leukemia 11/2020 - 03/2011
1	Hypoglycemia (Reactive Hypoglycemia) 01/2023
1	Birth Weight (Birth Weights) 01/2023
1	Placental Insufficiency 01/2023
1	Respiratory Insufficiency (Respiratory Failure) 01/2023
1	Hypertrophy 01/2020
1	Anemia 03/2014
1	Iron Deficiencies 03/2014
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2010
1	Nasopharyngeal Carcinoma 11/2009
1	Epstein-Barr Virus Infections 11/2009
1	Pneumonia (Pneumonitis) 12/2008
1	Respiratory Hypersensitivity 12/2008

Drug/Important Bio-Agent (IBA)

32	chromium hexavalent ionIBA 12/2023 - 01/2011
20	Drinking WaterIBA 05/2024 - 01/2011
8	Formaldehyde (Formol)FDA Link 11/2020 - 01/2008
7	CarcinogensIBA 01/2021 - 01/2011
3	folpet (Phaltan)IBA 01/2020 - 12/2017
3	CaptanIBA 01/2020 - 12/2017
3	EnzymesIBA 01/2020 - 01/2008
3	DNA (Deoxyribonucleic Acid)IBA 03/2019 - 01/2011
3	sodium bichromate (sodium dichromate)IBA 06/2013 - 01/2012
2	MetalsIBA 01/2020 - 08/2016
2	ethyl acrylateIBA 07/2018 - 07/2018
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 11/2014
2	Formaldehyde poisoningIBA 11/2009 - 08/2009
2	S-NitrosoglutathioneIBA 12/2008 - 01/2008
2	Bronchodilator Agents (Bronchodilators)IBA 12/2008 - 01/2008
1	tert-Butyl Alcohol (tert-Butanol)IBA 05/2024
1	FluorocarbonsIBA 01/2023
1	Liver GlycogenIBA 01/2023
1	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2023
1	Peroxisome ProliferatorsIBA 01/2020
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 10/2019
1	Hypoxia-Inducible Factor 1IBA 10/2019
1	cobalt sulfateIBA 08/2016
1	CobaltIBA 08/2016
1	ChromatesIBA 11/2014
1	Codon (Codons)IBA 06/2013
1	GATIBA 06/2013
1	IronIBA 01/2012
1	CytokinesIBA 01/2012
1	Sulfhydryl Compounds (Thiols)IBA 12/2008
1	Irritants (Vesicants)IBA 01/2008
1	Oxidoreductases (Dehydrogenase)IBA 01/2008
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 01/2008
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2008